Agranulocytosis after Use of Thiouracil

Observations on the use of thiouracil in rheumatoid arthritis.

No reports have been published on the possible effects upon rheumatoid arthritis of the thiouracil drugs, which have a potent action on the thyroid and also on the adrenal glands, although several investigators have pointed out certain correlations between disturbances of the thyroid on the one hand, and rheumatoid arthritis on the other, and the study of the adrenal cortex plays a central role...

report of one case of agranulocytosis after clozapine treatment

introduction : clozapine is the first effective antipsychotic drug with the least extra pyramidal side effects and more agranulocytosis than other standard neuroleptics. granolocytopenia or agranulocytosis occurs in 1 to 2 percent of all patients treated with clozapine. agranulocytosis due to clozapine is a fatal disorder that requires immediate clinical intervention.   method : this paper repo...

Thiouracil in Thyrotoxicosis

Agranulocytosis

Development of Agranulocytosis after Discontinuation of Methimazole: An Unusual Case

Agranulocytosis is a rare and critical adverse effect of antithyroid drugs (ATD). The occurrence of agranulocytosis in continuous ATD treatment patients is well known; however, a case of ATD agranulocytosis occurring following the discontinuation of methimazole (MMI) treatment is not a usual situation. We herein describe a case of a 41-year-old woman who was previously administered methimazole ...